|The CA9 sirt6 (Catalog #MBS2011410) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Carbonic Anhydrase IX (CA9) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CA9 sirt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CA9 sirt6 product has the following accession number(s) (GI #300797597) (NCBI Accession #NP_001180214.1) (Uniprot Accession #Q8N6T7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEFELRR Q-PL GEEDLPSEED SPREEDPPGE EDLPGEEDLP GEEDLPEVKP KSEEEGSLKL EDLPTVEAPG DPQEPQNNAH RDKEGDDQSH WRYGGDPPWP RVSPACAGRF QSPVDIRPQL AAFCPALRPL ELLGFQLPPL PELRLRNNGH SVQLTLPPGL EMALGPGREY RALQLHLHWG AAGRPGSEHT VEGHRFPAEI HVVHLSTAFA RVDEALGRPG GLAVLAAFLE EGPEENSAYE QLLSRLEEIA EEGSETQVPG LDISALLPSD FSRYFQYEGS LTTPPCAQGV IWTVFNQTVM LSAKQLHTLS DTLWGPGDSR LQLNFRATQP LNGRVIEASF PAGVDSSPRA AEPVQLNSCL AAGD.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Carbonic Anhydrase IX (CA9) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism: Homo sapiens (Human)
Expression System: Prokaryotic expression
Residues: Pro59~Asp414 (Accession # Q8N6T7) with two N-terminal Tags, His-tag and T7-tag. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Atherosclerosis, Breast Neoplasms, Carcinoma, Hepatocellular, Cardiomegaly, Hypertrophy, Immune System Diseases, Inflammation, Liver Diseases, Necrosis, Neoplasms are some of the diseases may be linked to Recombinant Carbonic Anhydrase IX (CA9). The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Prostate, Skin tissues are correlated with this protein.