CD127 protein product blog
Tags: Protein; CD127; CD127 protein;
The CD127 cd127 (Catalog #MBS666847) is a Protein produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. The CD127-muIg-Purified Preservative Free reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD127 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CD127 cd127 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The CD127 cd127 product has the following accession number(s) (GI #224697002) (NCBI Accession #CAM57334.1) (Uniprot Accession #B9ZSM5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
(1)kpqapel rgs(10) th e mature extracellu lar domain of human CD127 (IL-7Ra): (11)esgyaq ngdledaeld dysfscysql evngsqhslt cafedpdvni tnlefeicga lvevkclnfr klqeiyfiet kkflligksn icvkvgeksl tckkidltti vkpeapfdls vvyregandf vtfntshlqk kyvkvlmhdv ayrqekdenk wthvnlsstk ltllqrklqp aamyeikvrs ipdhyfkgfw sewspsyyfr tpeinnssge md(229) mu rine IgG2a Fc + hinge regions: (230)gtepr gptikpcppc kcpapnllgg psvfifppki kdvlmislsp ivtcvvvdvs eddpdvqisw fvnnvevhta qtqthredyn stlrvvsalp iqhqdwmsgk efkckvnnkd lpapiertis kpgsvrapqv yvlpppeeem tkkqvtltcm vtdfmpediy vewtnngkte lnykntepvl dsdgsyfmys klrvekknwv ernsyscsvv heglhnhhtt ksfsrtpgk( 464) (464 aa total). The molecule is dimeric with a predicted monomeric non glycosylat ed molecular weight of 52.8 kd.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including CD127 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Transfectant Cell Line: CHO
Performance: Recombinant soluble CD127-muIg was reactive with anti-CD127 clone 40131 as well as clone ANC8F2 in EIA and FACS. Production: Human CD127-muIg fusion protein was Protein A purified from (low FBS containing) tissue culture supernatant of CHO transfectants. Product was 0.2u sterile-filtered and vialed under aseptic conditions.
Buffer: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl. Product was sterile filtered under aseptic conditions. The following patways have been known to be associated with this gene. Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental, Hypersensitivity, Immune System Diseases, Inflammation, Liver Diseases, Lung Diseases, Multiple Sclerosis, Necrosis, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma are some of the diseases may be linked to CD127-muIg-Purified Preservative Free. Blood, Intestine, Liver, Lymph, Lymph Node, Muscle, Spleen, Thymus, Trachea tissues are correlated with this protein. CD127 also interacts with the following gene(s): IL2RG, IL7, JAK1, JAK2, JAK3, TYK2.