COCH recombinant protein product blog
Tags: Recombinant Protein; COCH; COCH recombinant protein; Cochlin;
The COCH coch (Catalog #MBS636113) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase.The COCH coch product has the following accession number(s) (GI #205277471) (NCBI Accession #NP_001128530.1) (Uniprot Accession #O43405). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Cochlin are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Activity: Measured by its ability to support the adhesion of SW1353 cells (human chondrosarcoma cells, ATCC: HTB-94). When 5x10e4 cells per well were added to rhCochlin coated plates (10ug/ml, 100ul/well) ~70-90% will adhere after 60 minutes at 37ºC. The protein also enhances IFNg secretion by anti-CD3 activated human T cells. COCH also interacts with the following gene(s): ANXA2, COL2A1, LIF, TECTB. Abnormalities, Multiple, Carcinoma, Cardiovascular Diseases, Congenital Abnormalities, Disease Models, Animal, Genital Diseases, Male, Inflammation, Myocardial Infarction, Neoplasms, Nervous System Diseases are some of the diseases may be linked to Cochlin, Recombinant, Human (COCH, Coagulation Factor C Homolog (Limulus polyphemus), COCH5B2, COCH-5B2, Cochlin Precursor, DFNA31, DFNA9, UNQ257/PRO294). Blood, Bone, Brain, Ear, Eye, Liver, Lung, Nerve, Skin, Spleen tissues are correlated with this protein.