|The COL6a1 col6a1 (Catalog #MBS2009059) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Collagen Type VI Alpha 1 (COL6a1) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the COL6a1 col6a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The COL6a1 col6a1 product has the following accession number(s) (GI #6753484) (NCBI Accession #NP_034063.1) (Uniprot Accession #Q04857). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-NLVWNA GAL HYSDEVEIIR GLTRMPSGRD ELKASVDAVK YFGKGTYTDC AIKKGLEELL IGGSHLKENK YLIVVTDGHP LEGYKEPCGG LEDAVNEAKH LGIKVFSVAI TPDHLEPRLS IIATDHTYRR NF.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Collagen Type VI Alpha 1 (COL6a1) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism: Mus musculus (Mouse)
Expression System: Prokaryotic expression
Residues: Asn82~Phe212 (Accession # Q04857) with N-terminal His-Tag. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. COL6a1 also interacts with the following gene(s): Col15a1, Col1a1, Col1a2, Col2a1, Col3a1, Col4a2, Col4a4, Col5a1, Col5a2, Col6a2. Bethlem myopathy, Brain Diseases, Disease Models, Animal, Fibrosis, Heart Defects, Congenital, Inflammation, Muscular Dystrophies, Neoplasms, Nervous System Diseases, Scleroatonic muscular dystrophy are some of the diseases may be linked to Recombinant Collagen Type VI Alpha 1 (COL6a1). Adipose Tissue, Bone, Connective Tissue, Embryonic Tissue, Heart, Joint, Kidney, Lung, Muscle, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene.