|The CX43 gja1 (Catalog #MBS2011823) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Connexin 43 (CX43) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CX43 gja1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CX43 gja1 product has the following accession number(s) (GI #6978896) (NCBI Accession #NP_036699.1) (Uniprot Accession #P08050). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-S LSAVYTCKRD PCPHQVDCFL SRPTEKTIFI IFMLVVSLVS LALNIIELFY VFFKGVKDRV KGRSDPYHAT TGPLSPSKDC GSPKYAYFNG CSSPTAPLSP MSPPGYKLVT GDRNNSSCRN YNKQASEQNW ANYSAEQNRM GQAGSTISNS HAQPFDFPDD NQNAKKVAAG HELQPLAIVD QRPSSRASSR ASSRPRPDDL EI.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Connexin 43 (CX43) with the following immunoassay(s):
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Connexin 43 (CX43) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism: Rattus norvegicus (Rat)
Expression System: Prokaryotic expression
Residues: Ser180~Ile382 (Accession # P08050) with two N-terminal Tags, His-tag and T7-tag. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. The following patways have been known to be associated with this gene. Arrhythmias, Cardiac, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Infertility, Male, Inflammation, Neoplasms, Oculodentodigital Dysplasia are some of the diseases may be linked to Recombinant Connexin 43 (CX43). Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Muscle, Ovary tissues are correlated with this protein.