|The IGF2 igf2 (Catalog #MBS845384) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s IGF-II can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE; HPLC. Researchers should empirically determine the suitability of the IGF2 igf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IGF2 igf2 product has the following accession number(s) (GI #4504609) (NCBI Accession #NP_000603.1) (Uniprot Accession #P01344). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including IGF-II are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility/Reconstitution Instructions: Reconstitute in 10 mM acetic acid to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and or stored at 4 degree C for 1 week or -20 degree C for future use.
Endotoxin Level: <0.1 ng/mug
Biological Activity: The recombinant human IGF-II is biologically active when compared to standard. The ED?? as determined by competitive binding against plasma-derived IGF-II to human placental membranes is <1.0 ng/ml, corresponding to a specific activity of >1 x 10 units/mg.
Results: <1.0 ng/ml
Handling: Centrifuge the vial prior to opening. IGF2 also interacts with the following gene(s): GPC3, IGF1R, IGF2BP2, IGF2R, IGFBP1, IGFBP2, IGFBP3, IGFBP5, IGFBP6, VEGFA. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Connective Tissue, Embryonic Tissue, Heart, Kidney, Liver, Muscle, Placenta tissues are correlated with this protein. Beckwith-Wiedemann Syndrome, Breast Neoplasms, Carcinoma, Hepatocellular, Colorectal Neoplasms, Growth Disorders, Kidney Diseases, Liver Diseases, Liver Neoplasms, Obesity, Wilms Tumor are some of the diseases may be linked to IGF-II, human recombinant.