IL-10 recombinant protein product blog
Tags: IL-10; Recombinant Protein; Interleukin-10; IL-10 recombinant protein;
The IL-10 il10 (Catalog #MBS553073) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.The IL-10 il10 product has the following accession number(s) (GI #6754318) (NCBI Accession #NP_034678.1) (Uniprot Accession #P18893). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MPGSALLCCL LLLTGMRISR GQYSREDNNC THFPVGQSHM LLELRTAFSQ VKTFFQTKDQ LDNILLTDSL MQDFKGYLGC QALSEMIQFY LVEVMPQAEK HGPEIKEHLN SLGEKLKTLR MRLRRCHRFL KCENKSKAVE QVKSDFNKLE DQGVYKAMNE FDIFINCIEA YMMIKMKS.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Interleukin-10 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Domain: four helix cytokine core
Host Note: Optimized DNA sequence encoding Mouse Interleukin-10 mature chain was expressed in Escherichia Coli. Endotoxin: Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight Note: Native Mouse Interleukin-10 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculated molecular mass of approximately 19 kDa.
Recombinant Mouse IL-10 is a disulfide-linked monomer protein consisting of 161 amino acid residue subunits, and migrates as an approximately 19 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Blood, Bone Marrow tissues are correlated with this protein. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Asthma, Colitis, Hypersensitivity, Immediate, Inflammation, Intestinal Diseases, Liver Diseases, Lung Diseases, Neoplasms, Sepsis are some of the diseases may be linked to Mouse Interleukin-10 Recombinant.