|The IL10 il10 (Catalog #MBS650378) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The IL10 il10 product has the following accession number(s) (GI #10835141) (NCBI Accession #NP_000563.1) (Uniprot Accession #P22301). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MSKGHSIKGD NNCTHFPVSQ THMLRELRAA FSQVKTFFQK KDQLDNILTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINYI EAYVTLKMKN.
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Biological Activity: The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is less than 10ng/ml.
Endotoxin Level: 0.1ng/ug (1EU/ug). Reconstitution: We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 degree C for 1 week or -20 degree C for future use. IL10 also interacts with the following gene(s): IL10RA, IL10RB. Blood, Connective Tissue, Lung, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Asthma, Colitis, Hypersensitivity, Immediate, Inflammation, Intestinal Diseases, Liver Diseases, Lung Diseases, Neoplasms, Sepsis are some of the diseases may be linked to Interleukin 10, Recombinant, Rat (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF).