IL31 recombinant protein product blog
Tags: Recombinant Protein; IL31; IL31 recombinant protein;
The IL31 il31 (Catalog #MBS5304068) is a Recombinant Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase.The IL31 il31 product has the following accession number(s) (GI #62122911) (NCBI Accession #NP_001014358.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including IL31 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
Endotoxin Levels: 0.01 ng/ug. Expression System: E Coli. Dermatitis, Dermatitis, Allergic Contact, Dermatitis, Atopic, Hypersensitivity, Inflammation, Lung Diseases, Lung Neoplasms, Melanoma, Necrosis, Respiratory Tract Diseases are some of the diseases may be linked to IL31 protein. IL31 also interacts with the following gene(s): IL28A, IL31RA, IL32, IL6ST, MUC5AC, OSMR, STAT3, TSLP.