ITGa8 recombinant protein product blog
Tags: Recombinant Protein; ITGA8; Integrin Alpha 8; ITGa8 recombinant protein;
The ITGa8 itga8 (Catalog #MBS2029660) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Integrin Alpha 8 can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). Researchers should empirically determine the suitability of the ITGa8 itga8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ITGa8 itga8 product has the following accession number(s) (GI #47717127) (NCBI Accession #NP_001001309.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Integrin Alpha 8 (ITGa8) with the following immunoassay(s):
Sequence Information
SDS-Page
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Integrin Alpha 8 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism Species: Homo sapiens (Human)
Source: Prokaryotic expression
Residues: Asp907~Ala1063
Tags: N-terminal His and GST Tag
Subcellular Location: Membrane. Traits: Freeze-dried powder
Predicted isoelectric point: 7.9
Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:
1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. Embryonic Tissue, Inner Ear, Kidney, Lung, Uterus tissues are correlated with this protein. Abnormalities, Multiple, Brain Diseases, Cell Transformation, Neoplastic, Congenital Abnormalities, Disease Models, Animal, Fibrosis, Hypertrophy, Inflammation, Kidney Diseases, Nervous System Diseases are some of the diseases may be linked to Recombinant Integrin Alpha 8 (ITGa8). The following patways have been known to be associated with this gene. ITGa8 also interacts with the following gene(s): Fn1, Itgb1, Itgb3, Itgb5, Itgb8.