KIR2DS4 recombinant protein product blog
Tags: Recombinant Protein; KIR2DS4; KIR2DS4 recombinant protein;
The KIR2DS4 kir2ds4 (Catalog #MBS536800) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s KIR2DS4 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the KIR2DS4 kir2ds4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The KIR2DS4 kir2ds4 product has the following accession number(s) (GI #116517309) (NCBI Accession #NP_036446.3) (Uniprot Accession #P43632). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MEGVHRKPSF LALPGHLVKS EETVILQCWS DVMFEHFLLH REGKFNNTLH LIGEHHDGVS KANFSIGPMM PVLAGTYRCY GSVPHSPYQL SAPSDPLDMV IIGLYEKPSL SAQPGPTVQA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAVRSINGTF QADFPLGPAT HGGTYRCFGS FRDAPYEWSN SSDPLLVSVT GN.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the KIR2DS4 protein with the following immunoassay(s):
SDS-PAGE (Figure annotation denotes ug of protein loaded and % gel used.)
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including KIR2DS4 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: An activating Killer Cell Ig-like Receptor (KIR, previously called p50 KIR, p50.3, cl39, or KAR-K1), which may recognize class I MHC molecules. The protein coding region of the extracellular domain of KIR2DS4 (amino acids 1-202) was cloned into an E Coli expression vector. The extracellular domain of KIR2DS4 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant KIR2DS4 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Expression System: E Coli. Blood tissues are correlated with this protein. The following patways have been known to be associated with this gene. Anemia, Carcinoma, Hepatocellular, Epstein-Barr Virus Infections, Kidney Diseases, Leukemia, Leukemia, Myeloid, Acute, Multiple Myeloma, Neoplasms, Experimental, Renal Insufficiency are some of the diseases may be linked to KIR2DS4 protein.