LIFR recombinant protein product blog
Tags: Recombinant Protein; LIFR; Lifr recombinant protein; LIFR/CD118;
The LIFR lifr (Catalog #MBS844245) is an Active Protein produced from HEK293 cells (Gin 45- Ser 833) and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s LIFR/CD118 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the LIFR lifr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The LIFR lifr product has the following accession number(s) (GI #189083786) (NCBI Accession #NP_001121143.1) (Uniprot Accession #P42702). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given active protein. We\'ve tested the Human CellExp LIFR / CD118, human recombinant with the following immunoassay(s):
Testing Data
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including LIFR/CD118 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility/Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 month. For extended storage, it is recommended to store at -20 degree C.
Endotoxin Level: <1 EU/mug by LAL method
Biological Activity: Measured by its ability to inhibit LIF-dependent proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 5-10 ug/ml in the presence of 0.3 ng/ml of recombinant human LIF. Brain, Embryonic Tissue, Ganglia, Heart, Liver, Muscle, Nerve, Placenta, Uterus, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. LIFR also interacts with the following gene(s): CNTFR, IL11, IL6ST, LIF, OSM. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Hypertrophy, Inflammation, Liver Diseases, Necrosis, Stuve-Wiedemann syndrome are some of the diseases may be linked to Human CellExp LIFR / CD118, human recombinant.