|The MPL mpl (Catalog #MBS2018696) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Myeloproliferative Leukemia Virus Oncogene (MPL) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the MPL mpl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MPL mpl product has the following accession number(s) (GI #171846242) (NCBI Accession #NP_001116421.1) (Uniprot Accession #Q08351). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- LYAYR GEKPRACPLY SQSVPTFGTR YVCQFPAQDE VRLFFPLHLW VKNVSLNQTL IQRVLFVDSV GLPAPPRVIK ARGGSQPGEL QIHWEAPAPE ISDFLRHELR YGPTDSSNAT APSVIQLLST ETCCPTLWMP NPVPVLDQPP CVHPTASQPH GPAPFLTVKG GSCLVSGLQA GKSYWLQLRS QPDGVSLRGS.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Myeloproliferative Leukemia Virus Oncogene (MPL) with the following immunoassay(s):
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Myeloproliferative Leukemia Virus Oncogene (MPL) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism: Mus musculus (Mouse)
Expression System: Prokaryotic expression
Residues: Leu66~Ser260 (Accession # Q08351) with two N-terminal Tags, His-tag and T7-tag
Subcellular Location: Membrane; Single-pass type I membrane protein. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
Predicted Isoelectric Point: 8.8
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. Anemia, Bone Marrow Diseases, Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Neoplasms, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytopenia, Thrombocytosis are some of the diseases may be linked to Recombinant Myeloproliferative Leukemia Virus Oncogene (MPL). The following patways have been known to be associated with this gene. Bone Marrow, Inner Ear, Mammary Gland, Spleen tissues are correlated with this protein.