OSM recombinant protein product blog
Tags: Recombinant Protein; OSM recombinant protein; OSM; Oncostatin M;
The OSM osm (Catalog #MBS651083) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase.The OSM osm product has the following accession number(s) (GI #10092621) (NCBI Accession #NP_065391.1) (Uniprot Accession #P13725). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Biological Activity: ED50 <2ng/ml (> 5x105units/mg). The biological activity is determined by measuring the oncostatin M concentration dependent stimulation of proliferation of TF-1 cells. The suggested concentration range for in vitro activity studies is 0.2-20.0ng/ml. The optimal concentration should be determined for each specific application. Oncostatin M is observed to exert variable, cell type dependent effects. For example, oncostatin M is observed to stimulate the growth of normal fibroblasts and AIDS-related Kaposi sarcoma cells, but is observed to inhibit the growth of A375 melanoma cells.
Endotoxin Level: ~0.1ng/ug. The following patways have been known to be associated with this gene. OSM also interacts with the following gene(s): IL6ST, LIFR, OSMR. Blood, Brain, Intestine, Kidney, Lung, Ovary, Thymus, Uncharacterized Tissue tissues are correlated with this protein. Cardiovascular Diseases, Immune System Diseases, Inflammation, Leukemia, Liver Diseases, Melanoma, Neoplasms, Neuroectodermal Tumors, Skin Diseases, Vascular Diseases are some of the diseases may be linked to Oncostatin M, Recombinant, Human (OSM).