PTPN6 recombinant protein product blog
Tags: Recombinant Protein; PTPN6 recombinant protein; PTPN6; SHP-1;
The PTPN6 ptpn6 (Catalog #MBS844577) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s SHP-1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the PTPN6 ptpn6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The PTPN6 ptpn6 product has the following accession number(s) (GI #18104989) (NCBI Accession #NP_002822.2) (Uniprot Accession #P29350). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MGFWEEFESL QKQEVKNLHQ RLEGQRPENK GKNRYKNILP FDHSRVILQG RDSNIPGSDY INANYIKNQL LGPDENAKTY IASQGCLEAT VNDFWQMAWQ ENSRVIVMTT REVEKGRNKC VPYWPEVGMQ RAYGPYSVTN CGEHDTTEYK LRTLQVSPLD NGDLIREIWH YQYLSWPDHG VPSEPGGVLS FLDQINQRQE SLPHAGPIIV HCSAGIGRTG TIIVIDMLME NISTKGLDCD IDIQKTIQMV RAQRSGMVQT EAQYKFIYVA IAQFIETTKK KLEVLQSQKG QESEYGNITY.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given active protein. We\'ve tested the Human Recombinant SHP-1 with the following immunoassay(s):
SDS-PAGE
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including SHP-1 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Source: E Coli
. Endotoxin Level: < 1.0 EU per 1 ug of protein (determined by LAL method)
Biological Activity: >5,000 units/mg of SHP-1.
Unit Definition: One unit will hydrolyze 1 nanomole of p-nitrophenylphosphatate (pNPP) per minute at pH 7.4 at 37 degree C using 10 mM of substrate.
Handling: Centrifuge the vial prior to opening. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Muscle, Skin, Spleen tissues are correlated with this protein. PTPN6 also interacts with the following gene(s): BLNK, EGFR, GAB1, SIRPA, SRC, SSTR2. Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Death, Immune System Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Lung Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Human Recombinant SHP-1. The following patways have been known to be associated with this gene.