|The rNAP 2 ppbp (Catalog #MBS145035) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The rNAP 2 ppbp product has the following accession number(s) (GI #24308468) (NCBI Accession #NP_714943.1) (Uniprot Accession #Q99ME0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Neutrophil Activating Protein-2 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized NAP-2 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is less than 10ng/ml, corresponding to a specific activity of 100,000units/mg. The following patways have been known to be associated with this gene. Asthma, Atherosclerosis, Carcinoma, Cardiovascular Diseases, Heart Diseases, Inflammation, Ischemia, Lung Diseases, Lung Neoplasms, Necrosis are some of the diseases may be linked to Recombinant Rat Neutrophil Activating Protein-2 (CXCL7). Mixed tissues are correlated with this protein. rNAP 2 also interacts with the following gene(s): Alb, Cxcl6, Fn1, Il8rb, Pf4, Plg.