SHH recombinant protein product blog
Tags: SHH; Recombinant Protein; SHH recombinant protein; Sonic hedgehog (SHH);
The SHH shh (Catalog #MBS845020) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Sonic Hedgehog (SHH) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE; HPLC. Researchers should empirically determine the suitability of the SHH shh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The SHH shh product has the following accession number(s) (GI #4506939) (NCBI Accession #NP_000184.1) (Uniprot Accession #Q15465). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Sonic Hedgehog (SHH) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility/Reconstitution Instructions: When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile H?O to a concentration of 0.1-0.5 mg/ml, which can be further diluted into other aqueous solutions.
Endotoxin Level: <0.01 ng/mug
Biological Activity: Human recombinant Sonic Hedgehog is biologically active as compared to a standard. The ED??, measured by the dose-dependent induction of alkaline phosphatase production by C3H/10T1/2 fibroblasts, is 750ng/ml.
Results: 750ng/ml.
Handling: Centrifuge the vial prior to opening. Brain, Intestine, Liver, Lung, Uncharacterized Tissue tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Carcinoma, Cardiovascular Diseases, Craniofacial Abnormalities, Disease Models, Animal, Holoprosencephaly, Holoprosencephaly 3, Neoplasm Metastasis, Neural Tube Defects are some of the diseases may be linked to Sonic Hedgehog (SHH), human recombinant. SHH also interacts with the following gene(s): BMP2, BMP4, GAS1, GLI1, GLI2, GLI3, GPC3, HHIP, PTCH1, PTCH2.