|The SNCa snca (Catalog #MBS2018674) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Synuclein Alpha (SNCa) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the SNCa snca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SNCa snca product has the following accession number(s) (GI #9507125) (NCBI Accession #NP_062042.1) (Uniprot Accession #P37377). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- KQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP SSEAYEMPSE EGYQDYEPEA.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Synuclein Alpha (SNCa) with the following immunoassay(s):
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Synuclein Alpha (SNCa) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Organism: Rattus norvegicus (Rat)
Expression System: Prokaryotic expression
Residues: Lys23~Ala140 (Accession # P37377) with N-terminal His-Tag. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4. SNCa also interacts with the following gene(s): Lrrk2, Mapt, Park2, Park7, Slc6a3, Sncaip, Stub1. Brain Diseases, Disease Models, Animal, Lewy Body Disease, Movement Disorders, Neoplasms, Nerve Degeneration, Nervous System Diseases, Neurodegenerative Diseases, Parkinson Disease, Parkinsonian Disorders are some of the diseases may be linked to Recombinant Synuclein Alpha (SNCa). The following patways have been known to be associated with this gene. Brain, Dorsal Root Ganglion, Eye, Heart, Liver, Prostate tissues are correlated with this protein.