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Troponin I native protein product blog

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Posted on 2017-11-26 20:00:43 by mybiosource_staff
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Tags: Troponin I; Native Protein; Troponin I native protein;
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The Troponin I n/a (Catalog #MBS5308434) is a Native Protein produced from Human Skeletal Muscle and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Troponin I n/a

Source Note: Human Skeletal Muscle
Protein type: native. Contaminants: non-detected
Biohazard: Tissue Donor was tested and found negative fo HBsAg, HIV-1 and HIV-2 anitbodies, HCV and Syphillis. However, because no test can guarantee absence of infectious material, use standard laboratory precautions.
Biological Significance: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein.
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