VTN recombinant protein product blog
Tags: vitronectin; VTN; Recombinant Protein; VTN recombinant protein;
The VTN vtn (Catalog #MBS2029640) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Vitronectin (VTN) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Vitronectin can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, WB.(May be suitable for use in other assays to be determined by the end user.). Researchers should empirically determine the suitability of the VTN vtn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VTN vtn product has the following accession number(s) (GI #88853069) (NCBI Accession #NP_000629.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Vitronectin (VTN) with the following immunoassay(s):
Sequence Information
SDS-Page
Source: Prokaryotic expression
Residues: Ala19~Glu111
Tags: N-terminal His Tag
Subcellular Location: Secreted, Extracellular matrix
Traits: Freeze-dried powder. Predicted isoelectric point: 4.7
Predicted Molecular Mass: 11.6kDa
Accurate Molecular Mass: 19kDa as determined by SDS-PAGE reducing conditions
Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:
1.Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleavedto give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. The following patways have been known to be associated with this gene. VTN also interacts with the following gene(s): ITGB3, MMP9, PLAUR, SERPINE1. Blood, Brain, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Pancreas, Placenta tissues are correlated with this protein. Carcinoma, Hepatocellular, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hepatitis, Kidney Diseases, Liver Diseases, Liver Neoplasms, Nervous System Diseases are some of the diseases may be linked to Recombinant Vitronectin (VTN).